Using the black goji fruit originally produced in Nuomuhong, Qinghai Province as raw material,and it is produced by 8 major technologies such as high-efficiency juice extraction,microwave ultrasonic wall-breaking extraction,vacuum degassing and anti-oxidation,high-pressure particle emulsification, and low-temperature sterilization.It realized the efficient extraction of bioactive substances such as proanthocyanidins,goji polysaccharides,vitamin C amino acids and various trace elements in black goji berry,solved the technical problems of difficult preservation and oxidation loss of proanthocyanidins in the natural environment,and maintained the proper flavor,color and nutritional contents of black wolfberry puree,to achieve the convenient drinking and efficient absorption of the product.